Mes données de santé
The information site for patients treated within the Unicancer network or included in Unicancer network clinical trials. 
Objectives

Une publication récente (Grippin et al., Nature, 22 octobre 2025) suggère une interaction immune synergique entre la vaccination mRNA COVID-19 et l’efficacité des inhibiteurs de checkpoint immunitaire (ICI), en particulier via des modifications des signatures IFN et de la réponse mémoire T préexistante.A ce jour aucune donnée n’existe en cohorte française sur patients en situation réelle (real-world) pour confirmer cette observation.

Data controller

Centre Léon Bérard

Categories of data used
Données d’identification (sans donnée nominative) / Données de santé
Origine de données utilisées
Soins
Centre Léon Bérard (Lyon)
2021
2022
Population subject to research or data processing

Critères d’inclusion : •patients pris en charge au CLB •mis sous anticorps anti-PD-1 entre 01/01/2021 et 01/01/2022•avec ou sans vaccination COVID-19 mRNA antérieure. Critères d’exclusion :•absence d’information fiable sur vaccination• traitement ICI hors anti-PD-1 exclusif

Legal basis

Exécution d’une mission d’intérêt public (lutte contre le cancer)

Internal and external data recipients

Professeur Jean Yves BLAY et Docteur Pierre HEUDEL

Research start date
30/10/2025
Data retention period

2 ans après la publication scientifique puis archivage sur un support distinct pour une durée conforme à la réglementation en vigueur

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If you believe, after contacting us, that your "Data Protection" rights are not being respected, you can file a complaint with the relevant data protection authority.