Mes données de santé
The information site for patients treated within the Unicancer network or included in Unicancer network clinical trials. 
Objectives

Primary :

  • Identify the determinants associated with HPD in patients treated with PD-1/PD-L1 blockade using a large database of comprehensive cancer centers (ConSoRe).

 

Secondary :

  • Describe the association between PD-L1 tumor IHC and HPD in patients treated with PD-1/PD-L1 blockade using a large database of comprehensive cancer centers (ConSoRe).
  • Describe the management of HPD in a large-scale real-life setting using a large database of comprehensive cancer centers (ConSoRe).
  • Correlate the occurrence of HPD with survival outcomes using log-rank test and multivariate analysis. 
Data controller

Institut Paoli Calmettes

232 Boulevard Sainte Marguerite

13273 Marseille Cedex 09

Categories of data used
Données d’identification (sans donnée nominative) / Données de santé
Origine de données utilisées
Soins
Institut Paoli Calmettes (Marseille)
Centre Jean Perrin (Clermont-Ferrand)
Institut Curie (Paris et Saint-Cloud)
Population subject to research or data processing

Inclusion criteria

  • Metastatic solid tumor (or Hodgkin disease)
  • Treatment with immune checkpoint inhibitor (alone or in combination)
  • Hyperprogressive disease confirmed by a radiological review.
  • ECOG 0-2
  • >18 years

 

Exclusion criteria :

  • Refusal to participate
Legal basis

Traitement de données mené dans l'intérêt public dans le domaine de la santé publique (article 6.1e et 9.2.j du Règlement (UE) n°2016/679)

Internal and external data recipients

Institut Paoli Calmettes

Research start date
25/01/2022
Data retention period

Les données seront conservées pendant la durée légale en vigueur ou tant qu'elles présenteront un intérêt scientifique 

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