Mes données de santé
The information site for patients treated within the Unicancer network or included in Unicancer network clinical trials. 
Objectives

Primaire :

To assess the progression-free survival (PFS) and OS (overall survival) in patients who receive PARPi as maintenance therapy after a platinum-sensitive relapse

Secondaires :

  • To assess the clinical, pathological, and molecular features correlated to treatment efficacy (PFS)
  • To evaluate the safety profile of PARPi in a real-world cohort
Data controller

Institut Paoli Calmettes

232 Boulevard Sainte Marguerite

13273 Marseille Cedex 09

Categories of data used
Données de santé / Données génétiques
Origine de données utilisées
Soins
Institut Paoli Calmettes (Marseille)
Others (excluding cancer centers)
Population subject to research or data processing

D’inclusion

  • Recurrent adenocarcinoma of the ovary, fallopian tubes, or peritoneum. Carcinosarcoma will also be allowed.
  • Time from prior platinum-based chemotherapy ≥ 6 months
  • Response to the last platinum-based regimen administered in the recurrent setting
  • Treatment with PARP inhibitor (olaparib, niraparib, or rucaparib) as maintenance after platinum-based chemotherapy will be included in the experimental group. Patients withour PARPi therapy after recurrence will be included as control
  • Female ≥ 18 years old

D’exclusion

  • Concomitant use of bevacizumab, immune checkpoint inhibitor or targeted therapies other than PARP inhibitors in the recurrent setting
Legal basis

Traitement de données mené dans l'intérêt public dans le domaine de la santé publique (article 6.1e et 9.2.j du Règlement (UE) n°2016/679)

Internal and external data recipients

Institut Paoli Calmettes

Research start date
18/10/2022
Data retention period

Les données seront conservées pendant la durée légale en vigueur ou tant qu'elles présenteront un intérêt scientifique 

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